We are using cookies to implement functions like login, shopping cart or language selection for this website. Furthermore we use Google Analytics to create anonymized statistical reports of the usage which creates Cookies too. You will find more information in our privacy policy.
OK, I agree I do not want Google Analytics-Cookies
The International Journal of Prosthodontics



Forgotten password?


Int J Prosthodont 31 (2018), No. 5     8. Oct. 2018
Int J Prosthodont 31 (2018), No. 5  (08.10.2018)

Page 481-484, doi:10.11607/ijp.5803, PubMed:30180236

Effect of Over-the-Counter Topical Agents on Denture-Induced Traumatic Lesions: A Clinical Study
Bural, Canan / Güven, Melahat Çelik / Kayacıoğlu, Büşra / Ak, Gülsüm / Bayraktar, Gülsen / Bilhan, Hakan
Purpose: To investigate the effects of over-the-counter products on the healing of dentureinduced ulcerations and patients' self-reported pain.
Materials and Methods: A total of 140 patients with acute denture-induced ulcerations were randomized into seven treatment groups: denture grinding (control); topical application of corn oil gel (placebo); triester glycerol oxide gel; D-panthenol gel; D-panthenol mouthwash; L-arginine mouthwash; and hyaluronic acid gel. Healing and self-reported pain were assessed after 1, 3, and 7 days of treatment.
Results: The percentage of healed lesions in the mandible and maxilla after 7 days was 67% and 65%, respectively. The only significance in healing was for mandibular lesions at 3 days after application of L-arginine mouthwash; at this period, the healing rate was significantly higher than d-panthenol gel, d-panthenol mouthwash, and hyaluronic acid gel (P < .05).
Conclusion: Denture grinding as the current protocol for acute denture-induced ulcerations should remain as the default.